Towards a Testbed for Dynamic Vehicle Routing Algorithms

Since modern transport services are becoming more flexible, demand-responsive, and energy/cost efficient, there is a growing demand for large-scale microscopic simulation platforms in order to test sophisticated routing algorithms. Such platforms have to simulate in detail, not only the dynamically changing demand and supply of the relevant service, but also traffic flow and other relevant transport services. This paper presents the DVRP extension to the open-source MATSim simulator. The extension is designed to be highly general and customizable to simulate a wide range of dynamic rich vehicle routing problems. The extension allows plugging in of various algorithms that are responsible for continuous re-optimisation of routes in response to changes in the system. The DVRP extension has been used in many research and commercial projects dealing with simulation of electric and autonomous taxis, demand-responsive transport, personal rapid transport, free-floating car sharing and parking search

Knowledge as a Predictor of Insurance Coverage Under the Affordable Care Act

Background: The Affordable Care Act established policy mechanisms to increase health insurance coverage in the United States. While insurance coverage has increased, 10%-15% of the US population remains uninsured. Objectives: To assess whether health insurance literacy and financial literacy predict being uninsured, covered by Medicaid, or covered by Marketplace insurance, holding demographic characteristics, attitudes toward risk, and political affiliation constant. Research Design: Analysis of longitudinal data from fall 2013 and spring 2015 including financial and health insurance literacy and key covariates collected in 2013. Subjects: A total of 2742 US residents ages 18-64, 525 uninsured in fall 2013, participating in the RAND American Life Panel, a nationally representative internet panel. Measures: Self-reported health insurance status and type as of spring 2015. Results: Among the uninsured in 2013, higher financial and health insurance literacy were associated with greater probability of being insured in 2015. For a typical uninsured individual in 2013, the probability of being insured in 2015 was 8.3 percentage points higher with high compared with low financial literacy, and 9.2 percentage points higher with high compared with low health insurance literacy. For the general population, those with high financial and health insurance literacy were more likely to obtain insurance through Medicaid or the Marketplaces compared with being uninsured. The magnitude of coefficients for these predictors was similar to that of commonly used demographic covariates. Conclusions: A lack of understanding about health insurance concepts and financial illiteracy predict who remains uninsured. Outreach and consumer-education programs should consider these characteristics

Are trade standards affecting the export-competitiveness of small and medium sized Egyptian agrifood exporters? The case of Egypt

With the increasing attention paid to the specification of food quality standards, food safety and quality are increasingly becoming major concerns for most countries. In the EU especially, public and private sectors respond to this by imposing tighter food safety requirements. The international fresh produce market has therefore become more competitive and sophisticated. JAFFEE AND HENSON (2005) point out that quality and safety have become the dominant modes of competition in the global market for high-value agri-food commodities. On top of the tariff-based trade barriers still in force, this presents additional challenges for developing countries and raises concerns about their ability to cope with these emerging qualitative export requirements

HIF-driven SF3B1 induces KHK-C to enforce fructolysis and heart disease.

Fructose is a major component of dietary sugar and its overconsumption exacerbates key pathological features of metabolic syndrome. The central fructose-metabolising enzyme is ketohexokinase (KHK), which exists in two isoforms: KHK-A and KHK-C, generated through mutually exclusive alternative splicing of KHK pre-mRNAs. KHK-C displays superior affinity for fructose compared with KHK-A and is produced primarily in the liver, thus restricting fructose metabolism almost exclusively to this organ. Here we show that myocardial hypoxia actuates fructose metabolism in human and mouse models of pathological cardiac hypertrophy through hypoxia-inducible factor 1α (HIF1α) activation of SF3B1 and SF3B1-mediated splice switching of KHK-A to KHK-C. Heart-specific depletion of SF3B1 or genetic ablation of Khk, but not Khk-A alone, in mice, suppresses pathological stress-induced fructose metabolism, growth and contractile dysfunction, thus defining signalling components and molecular underpinnings of a fructose metabolism regulatory system crucial for pathological growth

A MATSim scenario for autonomous vehicles in La Défense and Île-de-France

The synthesis of a scenario for the agent-based traffic simulation framework MATSim for the Île-de-France region is documented. A reduction of the scenario to an area around La Défense in Paris is proposed and next steps towards a study of autonomous vehicle fleets in that area are shown

Agent-based simulation of autonomous taxi services with dynamic demand responses

An agent-based simulation approach is presented, which makes it possible to capture the dynamic interplay between a supply of autonomous vehicle fleets with distinct operational schemes and a population of artificial persons based on an established multiagent traffic simulation framework. The simulation is able to show how agents react to the new travel options and make consistent decisions based on a well-defined framework of utility scoring.ISSN:1877-050